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Study finds light sensor in eyes control body's internal clock PDF
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Ophthalmology and Optometry
Thursday, 07 August 2008
Scientists have discovered the function of a third type of light sensor in the eye, related not to vision, but to control of the body's internal clock.

The investigators believe the discovery may offer a new pathway for potential treatments of light-related mood and sleep disorders. The sensors, found in two percent of retinal cells, are dedicated to detecting the presence and intensity of light through the use of a light-sensitive molecule called melanopsin, according to the report of the study results in the journal PLoS ONE.

Nocturnal mice in the study that did not have the sensor were unable to reset their internal biological clocks and thus woke up one-half hour earlier every evening, without adjusting to a 24-hour day. Project leader Satchin Panda of the Regulatory Biology Laboratory at the Salk Institute for Biological Studies in La Jolla, CA, said that searches of the recently sequenced mouse and human genomes revealed that both contained an extra light sensor gene.

The researchers narrowed the sensor's location to a small number of retinal cells and genetically engineered mice with sensor cells sensitive to a particular toxin. When the mice were exposed to the toxin, only the cells containing melanopsin died. The animals could still see normally and retained depth perception, but they became unable to discern and respond to light intensity.

The results confirm those of a separate study reported earlier this year in the journal Nature.
Allergan Receives U.S. FDA Approval for TRIVARIS PDF
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Product News
Thursday, 07 August 2008
The U.S. Food and Drug Administration (FDA) has recently approved TRIVARIS (triamcinolone acetonide injectable suspension) 80 mg/mL, a synthetic glucocorticoid corticosteroid with anti-inflammatory action. Delivered via intravitreal injection, the ophthalmic indications for TRIVARIS include sympathetic ophthalmia, temporal arteritis, uveitis, and ocular inflammatory conditions unresponsive to topical corticosteroids. These are inflammatory conditions that can result in vision loss.

"Retinal diseases are currently the leading cause of blindness in developed countries and represent a significant unmet need in eye care," said Scott Whitcup, M.D., Allergan's Executive Vice President, Research and Development.

"TRIVARISâ„¢ marks the first approval for Allergan resulting from our strategic focus on the development of therapies for back-of-the-eye diseases, and we remain committed to bringing forth innovative new treatments for patients suffering from retinal diseases."
AMD in an Asian Population PDF
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Ophthalmology and Optometry
Wednesday, 06 August 2008
AMD erodes and can eventually destroy the central vision needed for reading, driving, and other daily tasks. When AMD risk levels among racial and ethnic groups are compared, Caucasians are usually identified as at highest risk. Asians in particular have been assumed to have lower risk. Recently Ryo Kawasaki, MD, and colleagues compared the prevalence of early and late AMD in approximately 4,000 residents of Funagata, Japan, to the rate in white participants in the Australian Blue Mountains Eye Study (BMES); diagnostic definitions were identical in the two studies and age standardization enhanced data comparability. Importantly, the Funagata study is the first in a Japanese population to confirm a link between smoking and AMD prevalence.

The overall AMD prevalence rate in right eyes was 4.1 percent for the Funagata study, very close to the BMES rate of 4.4.percent. Prevalence of late AMD in men was also comparable for the two groups, 1.1 percent for Funagata participants and 1.2 percent for BMES, but was markedly different for the two groups of women: 0.3 percent and 2.1 percent, respectively. The authors note that these findings need to be confirmed by larger studies in Asian populations. Two earlier studies also found a higher prevalence of late AMD in Asian men, in contrast with most studies in Caucasians where rates are higher for women. The authors think a key reason may be that 36.8 percent of the Funagata men smoked, but only 2.8 percent of the women. In the BMES study, 14.4 percent of women were smokers. While many Asian men smoke, the habit is less socially acceptable for women. “As smoking is a well-recognized, modifiable AMD risk factor, smoking cessation is an important public health measure to reduce AMD, particularly among Japanese men,” Dr. Kawasaki says.

Source: AAO
Promotion the Italian way... PDF
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Feature Story
Wednesday, 06 August 2008
The Italian optical retail owner, Sara Nicoletti (picture), thought it would be a good idea to promote her business with a photo model. Since she found herself to be good looking she did the job herself...and topless!

Look at the picture and judge for yourself. According to Sara her business has improved considerably!

New Optical Fair in Vietnam PDF
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International News
Tuesday, 05 August 2008
A new optical fair will debut in Vietnam in November. Called International Optical Vietnam or 'iOV 2008', the first edition of the exhibition will be held Nov. 14 to 16, 2008 at the International Exhibition and Convention Center here.

The show is being organized by Vietman trade fair specialists, World Trade Fair Ltd in association with the VCCI Exhibition Service Company the exhibition organization of Vietnam Chamber of Commerce and Industry.

The show will include exhibitors in all categories of optical, from instruments and equipment to spectacle lenses, eyewear and contact lenses as well as shop and merchandising equipment and consulting services.

According to the organisers, Vietnam has a largely underdeveloped optical professional service and industry sector but the country is growing and with a population of over 84 million people, is the second fastest growing economy in the world after China, with GDP growth rate reached 8.48 percent last year.
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